500L Double-Pass RO Pharmaceutical Water Purification System Exported to Russia
This 500 L double-pass pharmaceutical water system is precisely customized to meet the purified-water requirements of Russian pharmaceutical production. It adopts a two-stage reverse osmosis (RO) + EDI deep deionization process, providing step-by-step purification of the feed water while achieving both high-efficiency impurity rejection and deep ionic removal. The system strictly complies with the European Pharmacopoeia (EP) and Russian GOST pharmaceutical water standards, supplying stable, high-purity process water for key applications such as API manufacturing and injectable production—building a solid quality foundation from the source.
Core Technologies
Dual-Stage RO Purification System
Online CIP/SIP Cleaning & Sterilization System
An integrated CIP (Clean-in-Place) and SIP (Sterilize-in-Place) system is installed in the piping, membrane modules, and storage units. Using 121 °C saturated pure steam circulation for sterilization combined with food-grade acid/alkali cleaning solutions, it thoroughly destroys residual microorganisms and pyrogens. Sanitary steam traps and condensate recovery devices ensure no secondary contamination during cleaning and sterilization while enabling condensate reuse for energy efficiency.
The entire system features a modular design integrating raw-water pretreatment, double-pass RO purification, sterile storage, and distribution circulation. It is compact, easy to assemble/disassemble, and fully compliant with GMP requirements for equipment layout and hygienic standards—well suited to the space planning and cleanroom grades of Russian pharmaceutical plants.
Key Technical Advantages
- High-Purity Compliance
The RO + EDI combined process achieves ≥ 99.9% removal of pyrogens and microorganisms. The product water fully complies with USP, EP, and Russian GOST R 52501-2005 standards for pharmaceutical water and can be used directly for injectables and API production. - High Efficiency & Energy Saving
With heat-recovery and condensate-reuse technologies, power consumption is as low as 0.8 kWh per ton of water, saving over 30% compared with traditional single-pass RO systems. The 304/316L stainless-steel construction offers excellent corrosion resistance and durability, extending service life to 8–10 years. With a water recovery rate of ≥ 75%, long-term operating and consumable costs are significantly reduced. - Intelligent & Stable Operation
Equipped with a Russian-language PLC control system, the unit supports one-touch start/stop, real-time parameter monitoring, and fault alarms. Data can be synchronized to a cloud management platform, matching the operation habits of local Russian maintenance teams. Remote technical-support interfaces ensure continuous and stable operation.